In this issue, Dr. Stoyan Borisov presents his clinical assessment study on the effect of Coriolus versicolor supplementation on patients with Low-risk and High-risk HPV subtypes. Dr. Chris Newton (Ph.D) proposes a study on the potential role of mushroom nutrition as modulators of toll receptor-mediated immune response.
The enzyme researcher, Dr. Amin Karmali (Ph.D) presents a detoxification analysis (in vitro) on mushroom nutrition, outlining the superoxide dismutase activity, cytochrome P450, cytochrome P450 reductase and secondary metabolites activity of Grifola frondosa (Maitake), Ganoderma lucidum (Reishi), Coriolus versicolor and Cordyceps sinensis.
Finally, the latest poster presentation on the efficacy of Coriolus versicolor in the treatment of HPV lesions (LSIL), presented by Dr. J.Silva Couto at the 14th World Congress of Cervical Pathology and Colpscopy- (IFCPC)-July 4th to 7th, 2011 in Rio de Janeiro, Brasil.
In this issue two articles were submitted by a team of researchers based in the University of Catania (Italy) focused on the potential use of mushroom nutrition in neurodegenerative disease. The basis for hypothesis is due to the enzyme activity that offsets the reactive oxygen species associated with the onset of Parkinson’s, Alzheimer´s disease and ALS.
The articles are:
Mushroom Nutrition as a Target for Novel Therapeutic Strategies: Relevance to Nutritional Approaches and Antioxidant Redox Modulation in Ant-Ageing Medicine- Professor Vittorio Calabrese et al.
Comparative Enzyme Analysis of Polyporus umbellatus, Agaricus blazei, Pleurtous osteratus and Hericium erinaceus-Carolin Cornelius et al.
This issue closes with a poster presentation entitled:
Coriolus versicolor Supplementation as Immunonutrition in HPV Patients with Cervical Lesions (LSIL)-by Dr. Jose Silva Couto-Institute of Oncology, Coimbra Portugal.
The poster is an evaluation of the efficacy of Coriolus versicolor supplementation in patients infected with HPV with low-grade squamous intraepithelial lesions (LSIL). The article describes how Coriolus versicolor supplementation (3g /day) over a period of one year substantially increased regression of the dysplasia (LSIL) and induced clearance of the high risk sub-types of the HPV virus responsible for cervical cancer.
The Clinical Journal of Mycology (formerly Mycology News) is dedicated to the dissemination of information on the clinical use of mushroom nutrition to health care practitioners. In this issue we address the role of Coriolus versicolor in the treatment of CIN-1 (LSIL HPV) and Herpes Simplex.
Dr J Silva Couto outlines the difference between LSIL and HSIL HPV and provides a protocol for use by medical professionals. In addition, Prof Amin Karmali explains the enzymatic qualities of Coriolus versicolor and how such attributes assist the immune system. Finally, Dr. Andrew French outlines his clinical experience using Coriolus versicolor in patients with herpes simplex with a recommended protocol for consultants.